IKZF1 deletion is associated with a poor outcome in pediatric B-cell precursor acute lymphoblastic leukemia in Japan

Genetic alterations of Ikaros family zinc finger protein 1 (IKZF1), point mutations in Janus kinase 2 (JAK2), and overexpression of cytokine receptor-like factor 2 (CRLF2) were recently reported to be associated with poor outcomes in pediatric B-cell precursor (BCP)-ALL. Herein, we conducted genetic...

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Main Authors: Asai, Daisuke, Imamura, Toshihiko, Suenobu, So-ichi, Saito, Akiko, Hasegawa, Daiichiro, Deguchi, Takao, Hashii, Yoshiko, Matsumoto, Kimikazu, Kawasaki, Hirohide, Hori, Hiroki, Iguchi, Akihiro, Kosaka, Yoshiyuki, Kato, Koji, Horibe, Keizo, Yumura-Yagi, Keiko, Hara, Junichi, Oda, Megumi
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2013
Teme:
Cancer Prevention
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699852/
https://ncbi.nlm.nih.gov/pubmed/23930217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.87
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