Arginase as a Mediator of Diabetic Retinopathy

We have shown previously that diabetes causes increases in retinal arginase activity that are associated with impairment of endothelial cell (EC)-dependent vasodilation and increased formation of the peroxynitrite biomarker nitrotyrosine. Arginase blockade normalizes vasodilation responses and reduc...

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Detalhes bibliográficos
Main Authors: Patel, Chintan, Rojas, Modesto, Narayanan, S. Priya, Zhang, Wenbo, Xu, Zhimin, Lemtalsi, Tahira, Jittiporn, Kanjana, Caldwell, R. William, Caldwell, Ruth B.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699717/
https://ncbi.nlm.nih.gov/pubmed/23840196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00173
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