Genetic Polymorphisms of the CASP8 Gene Promoter May Not Be Associated with Colorectal Cancer in Han Chinese from Southwest China

PURPOSE: Caspase 8 (CASP8) plays a critical role in the apoptotic pathway and aberrant regulation of this pathway causes many diseases including cancers. Genetic variants rs3834129 (CTTACT/−) and rs3769821 (T/C) in the promoter region of the CASP8 gene were documented to be associated with multiple...

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Autores principales: Xiao, Mei-Sheng, Chang, Le, Li, Wen-Liang, Du, Yong-Sheng, Pan, Yue, Zhang, Deng-Feng, Wen, Yu, Luo, Juan, Li, Xiao-Yan, Yao, Yong-Gang
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699664/
https://ncbi.nlm.nih.gov/pubmed/23844036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067577
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