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Effects of the Smad4 C324Y mutation on thyroid cell proliferation

Smad4 is a key mediator of the transforming growth factor-β (TGF-β) superfamily that is involved in the control of cell proliferation and differentiation. We recently demonstrated that a Smad4 mutation, Smad4 C324Y, isolated from nodal metastases of papillary thyroid carcinoma, causes an increase of...

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Autores principales: D’INZEO, SONIA, NICOLUSSI, ARIANNA, NARDI, FRANCESCO, COPPA, ANNA
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699576/
https://ncbi.nlm.nih.gov/pubmed/23591524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2013.1908
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