Mouse Tbx3 Mutants Suggest Novel Molecular Mechanisms for Ulnar-Mammary Syndrome

The transcription factor TBX3 plays critical roles in development and TBX3 mutations in humans cause Ulnar-mammary syndrome. Efforts to understand how altered TBX3 dosage and function disrupt the development of numerous structures have been hampered by embryonic lethality of mice bearing presumed nu...

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Bibliographic Details
Main Authors: Frank, Deborah U., Emechebe, Uchenna, Thomas, Kirk R., Moon, Anne M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699485/
https://ncbi.nlm.nih.gov/pubmed/23844108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067841
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