Somatic Mutation Profiling and Associations With Prognosis and Trastuzumab Benefit in Early Breast Cancer

BACKGROUND: Certain somatic alterations in breast cancer can define prognosis and response to therapy. This study investigated the frequencies, prognostic effects, and predictive effects of known cancer somatic mutations using a randomized, adjuvant, phase III clinical trial dataset. METHODS: The Fi...

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Hauptverfasser: Loi, Sherene, Michiels, Stefan, Lambrechts, Diether, Fumagalli, Debora, Claes, Bart, Kellokumpu-Lehtinen, Pirkko-Liisa, Bono, Petri, Kataja, Vesa, Piccart, Martine J., Joensuu, Heikki, Sotiriou, Christos
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699437/
https://ncbi.nlm.nih.gov/pubmed/23739063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djt121
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