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Drugs for solid cancer: the productivity crisis prompts a rethink

Despite remarkable progress in cancer-drug discovery, the delivery of novel, safe, and sustainably effective products to the clinic has stalled. Using Src as a model, we examine key steps in drug development. The preclinical evidence on the relationship between Src and solid cancer is in sharp contr...

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Autori principali: Rösel, Daniel, Brábek, Jan, Veselý, Pavel, Fernandes, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699349/
https://ncbi.nlm.nih.gov/pubmed/23836990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S45177
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