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cell type–specific gene expression differences in complex tissues

We describe cell type–specific significance analysis of microarrays (cssam) for analyzing differential gene expression for each cell type in a biological sample from microarray data and relative cell-type frequencies. first, we validated cssam with predesigned mixtures and then applied it to whole-b...

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Bibliographische Detailangaben
Hauptverfasser: Shen-Orr, Shai S, Tibshirani, Robert, Khatri, Purvesh, Bodian, Dale L, Staedtler, Frank, Perry, Nicholas M, Hastie, Trevor, Sarwal, Minnie M, Davis, Mark M, Butte, Atul J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699332/
https://ncbi.nlm.nih.gov/pubmed/20208531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1439
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