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DEVELOPMENTAL CIGARETTE SMOKE EXPOSURE: KIDNEY PROTEOME PROFILE ALTERATIONS IN LOW BIRTH WEIGHT PUPS

The Brenner hypothesis states that a congenital reduction in nephron number predisposes to adult-onset hypertension and renal failure. The reduction in nephron number induced by proportionally smaller kidney mass may predispose offspring to glomerular hyperfiltration with maturity onset obesity. Dev...

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Detalhes bibliográficos
Main Authors: Rekha, J, Chen, Jing, Canales, Lorena, Birtles, Todd, Pisano, M. Michele, Neal, Rachel E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699329/
https://ncbi.nlm.nih.gov/pubmed/22595367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2012.04.015
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