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Zebrafish rhabdomyosarcoma reflects the developmental stage of oncogene expression during myogenesis

Rhabdomyosarcoma is a pediatric malignancy thought to arise from the uncontrolled proliferation of myogenic cells. Here, we have generated models of rhabdomyosarcoma in the zebrafish by inducing oncogenic KRAS(G12D) expression at different stages during muscle development. Several zebrafish promoter...

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書誌詳細
主要な著者: Storer, Narie Y., White, Richard M., Uong, Audrey, Price, Emily, Nielsen, G. Petur, Langenau, David M., Zon, Leonard I.
フォーマット: Artigo
言語:Inglês
出版事項: Company of Biologists 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699286/
https://ncbi.nlm.nih.gov/pubmed/23821038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.087858
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