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Zebrafish rhabdomyosarcoma reflects the developmental stage of oncogene expression during myogenesis

Rhabdomyosarcoma is a pediatric malignancy thought to arise from the uncontrolled proliferation of myogenic cells. Here, we have generated models of rhabdomyosarcoma in the zebrafish by inducing oncogenic KRAS(G12D) expression at different stages during muscle development. Several zebrafish promoter...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Storer, Narie Y., White, Richard M., Uong, Audrey, Price, Emily, Nielsen, G. Petur, Langenau, David M., Zon, Leonard I.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Company of Biologists 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699286/
https://ncbi.nlm.nih.gov/pubmed/23821038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.087858
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