Selective linkage disruption in human-Chinese hamster cell hybrids: deletion mapping of the leuS, hexB, emtB, and chr genes on human chromosome 5.

Chinese hamster-human interspecific hybrid cells, which contain human chromosome 5 and express four genes linked on that chromosome, were subjected to selective conditions requiring them to retain one of the four linked genes, leuS (encoding leucyl-tRNA synthetase), but lose another, either emtB (en...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Dana, S, Wasmuth, J J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1982
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369921/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7177110/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.2.10.1220-1228.1982
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