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DOWN-REGULATION OF LRRK2 IN CONTROL AND DAT TRANSFECTED HEK CELLS INCREASES MANGANESE-INDUCED OXIDATIVE STRESS AND CELL TOXICITY

The extra-pyramidal symptoms associated with manganism often overlap with that seen in Parkinsonism suggesting a common link between the two disorders. Since wide deviations are observed in susceptibility and characteristics of the symptoms observed in manganism, these differences may be due to unde...

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Autors principals: Roth, Jerome A., Eichhorn, Michelle
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698986/
https://ncbi.nlm.nih.gov/pubmed/23628791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2013.04.008
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