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Mutations affecting the structure and function of immunoglobulin M.

Using a hybridoma cell line which secretes hapten-specific immunoglobulin M (IgM), we have isolated a variety of mutants which produce abnormal immunoglobulin. Immunoglobulin was tested for the size and composition of the component heavy and light chains and for variable and constant region related...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Shulman, M J, Heusser, C, Filkin, C, Köhler, G
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1982
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369896/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6817080/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.2.9.1033-1043.1982
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