Upregulation of the Angiotensin-Converting Enzyme 2/Angiotensin-(1-7)/Mas Receptor Axis in the Heart and the Kidney of Growth Hormone Receptor knock-out Mice

OBJECTIVE: Growth hormone (GH) resistance leads to enhanced insulin sensitivity, decreased systolic blood pressure and increased lifespan. The aim of this study was to determine if there is a shift in the balance of the renin-angiotensin system (RAS) towards the ACE2/Ang-(1-7)/Mas receptor axis in t...

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Hlavní autoři: GIANI, Jorge F., MIQUET, Johanna G., MUÑOZ, Marina C., BURGHI, Valeria, TOBLLI, Jorge E., MASTERNAK, Michal M., KOPCHIC, John J., BARTKE, Andrzej, TURYN, Daniel, DOMINICI, Fernando P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698955/
https://ncbi.nlm.nih.gov/pubmed/22947377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ghir.2012.08.003
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