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ROS play a critical role in the differentiation of alternatively activated macrophages and the occurrence of tumor-associated macrophages

Differentiation to different types of macrophages determines their distinct functions. Tumor-associated macrophages (TAMs) promote tumorigenesis owing to their proangiogenic and immune-suppressive functions similar to those of alternatively activated (M2) macrophages. We report that reactive oxygen...

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Autori principali: Zhang, Yan, Choksi, Swati, Chen, Kun, Pobezinskaya, Yelena, Linnoila, Ilona, Liu, Zheng-Gang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698641/
https://ncbi.nlm.nih.gov/pubmed/23752925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.75
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