Biological effects and clinical significance of lenalidomide-induced tumour flare reaction in patients with chronic lymphocytic leukaemia: in vivo evidence of immune activation and antitumour response

Lenalidomide has demonstrated impressive antileukaemic effects in patients with chronic lymphocytic leukaemia (CLL). The mechanism(s) by which it mediates these effects remain unclear. Clinically, CLL patients treated with lenalidomide demonstrate an acute inflammatory reaction, the tumour flare rea...

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Main Authors: Chanan-Khan, Asher A., Chitta, Kasyapa, Ersing, Noreen, Paulus, Aneel, Masood, Aisha, Sher, Taimur, Swaika, Abhisek, Wallace, Paul K., Mashtare, Terry L., Wilding, Greg, Lee, Kelvin, Czuczman, Myron S., Borrello, Ivan, Bangia, Naveen
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698616/
https://ncbi.nlm.nih.gov/pubmed/22010965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2011.08882.x
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