Direct reprogramming of mouse fibroblasts to cardiomyocyte-like cells using Yamanaka factors on engineered poly(ethylene glycol) (PEG) hydrogels

Direct reprogramming strategies enable rapid conversion of somatic cells to cardiomyocytes or cardiomyocyte-like cells without going through the pluripotent state. A recently described protocol couples Yamanaka factor induction with pluripotency inhibition followed by BMP4 treatment to achieve rapid...

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Autori principali: Smith, Amanda W., Hoyne, Jake D., Nguyen, Peter K., McCreedy, Dylan A., Aly, Haytham, Efimov, Igor R., Rentschler, Stacey, Elbert, Donald L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698604/
https://ncbi.nlm.nih.gov/pubmed/23773820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.05.050
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