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Ventilation with ‘clinically-relevant’ high tidal volumes does not promote stretch-induced injury in the lungs of healthy mice

OBJECTIVE: Ventilator-induced lung injury is a crucial determinant of the outcome of mechanically ventilated patients. Increasing numbers of mouse studies have identified numerous pathways and mediators that are modulated by ventilation, but it is conceptually difficult to reconcile these into a sin...

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Detalhes bibliográficos
Main Authors: Wilson, Michael R., Patel, Brijesh V., Takata, Masao
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698535/
https://ncbi.nlm.nih.gov/pubmed/22890257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e31825b91ef
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