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First ruthenium organometallic complex of antibacterial agent ofloxacin. Crystal structure and interactions with DNA

Organometallic ruthenium complex of quinolone antibacterial agent ofloxacin [(η(6)-p-cymene)RuCl(O,O-oflo)]·2.8H(2)O (1·2.8H(2)O) was isolated and its crystal structure was determined. In this »piano-stool« complex, quinolone is bidentately coordinated to the metal through the ring carbonyl and one...

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Detalhes bibliográficos
Main Authors: Turel, Iztok, Kljun, Jakob, Perdih, Franc, Morozova, Elena, Bakulev, Vladimir, Kasyanenko, Nina, Byl, Jo Ann W., Osheroff, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698415/
https://ncbi.nlm.nih.gov/pubmed/20973588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ic101355d
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