The LIM Homeodomain Protein Lhx6 Regulates Maturation of Interneurons and Network Excitability in the Mammalian Cortex

Deletion of LIM homeodomain transcription factor-encoding Lhx6 gene in mice results in defective tangential migration of cortical interneurons and failure of differentiation of the somatostatin (Sst)- and parvalbumin (Pva)-expressing subtypes. Here, we characterize a novel hypomorphic allele of Lhx6...

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Autori principali: Neves, Guilherme, Shah, Mala M., Liodis, Petros, Achimastou, Angeliki, Denaxa, Myrto, Roalfe, Grant, Sesay, Abdul, Walker, Matthew C., Pachnis, Vassilis
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2013
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698365/
https://ncbi.nlm.nih.gov/pubmed/22710612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhs159
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