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Adaptation of a retrovirus as a eucaryotic vector transmitting the herpes simplex virus thymidine kinase gene.

We investigated the feasibility of using retroviruses as vectors for transferring DNA sequences into animal cells. The thymidine kinase (tk) gene of herpes simplex virus was chosen as a convenient model. The internal BamHI fragments of a DNA clone of Moloney leukemia virus (MLV) were replaced with a...

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Publicat a:Mol Cell Biol
Autors principals: Tabin, C J, Hoffmann, J W, Goff, S P, Weinberg, R A
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1982
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369806/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6180306/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.2.4.426-436.1982
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