Retained organic solutes, patient characteristics and all-cause and cardiovascular mortality in hemodialysis: results from the retained organic solutes and clinical outcomes (ROSCO) investigators

BACKGROUND: Multiple solutes are retained in uremia, but it is currently unclear which solutes are toxic. Small studies suggest that protein-bound solutes, such as p-cresol sulfate and indoxyl sulfate and intracellular solutes, such as methylamine (MMA) and dimethylamine (DMA), may be toxic. Our obj...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Melamed, Michal L, Plantinga, Laura, Shafi, Tariq, Parekh, Rulan, Meyer, Timothy W, Hostetter, Thomas H, Coresh, Josef, Powe, Neil R
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698023/
https://ncbi.nlm.nih.gov/pubmed/23806101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2369-14-134
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