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An open-label randomized clinical trial of prophylactic paracetamol coadministered with 7-valent pneumococcal conjugate vaccine and hexavalent diphtheria toxoid, tetanus toxoid, 3-component acellular pertussis, hepatitis B, inactivated poliovirus, and Haemophilus influenzae type b vaccine

BACKGROUND: In two clinical trials, low-grade fever was observed more frequently after coadministration than after separate administration of two recommended routine pediatric vaccines. Since fever is an important issue with vaccine tolerability, we performed this open-label study on the efficacy an...

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Autores principales: Rose, Markus A, Juergens, Christine, Schmoele-Thoma, Beate, Gruber, William C, Baker, Sherryl, Zielen, Stefan
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698010/
https://ncbi.nlm.nih.gov/pubmed/23786774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2431-13-98
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