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Expression and significance of HMGB1, TLR4 and NF-κB p65 in human epidermal tumors

BACKGROUND: High mobility group protein box 1 (HMGB1) is a DNA binding protein located in nucleus. It is released into extracellular fluid where it acts as a novel proinflammatory cytokine which interacts with Toll like receptor 4 (TLR4) to activate nuclear factor-κB (NF-κB). This sequence of events...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Weng, Hui, Deng, Yunhua, Xie, Yuyan, Liu, Hongbo, Gong, Feili
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697986/
https://ncbi.nlm.nih.gov/pubmed/23803172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-311
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