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Striatal CB(1) and D(2) receptors regulate expression of each other, CRIP1A and delta opioid systems

Although biochemical and physiological evidence suggests a strong interaction between striatal CB(1) cannabinoid (CB(1)R) and D(2) dopamine (D(2)R) receptors, the mechanisms are poorly understood. We targeted medium spiny neurons of the indirect pathway using shRNA to knockdown either CB(1)R or D(2)...

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Detalhes bibliográficos
Main Authors: Blume, Lawrence C., Bass, Caroline E., Childers, Steven R., Dalton, George D., Roberts, David C. S., Richardson, Jasmine M., Xiao, Ruoyu, Selley, Dana E., Howlett, Allyn C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697910/
https://ncbi.nlm.nih.gov/pubmed/23286559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12139
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