Single-copy and amplified CAD genes in Syrian hamster chromosomes localized by a highly sensitive method for in situ hybridization.

Syrian hamster cells resistant to N-(phosphonacetyl)-L-aspartate (PALA), a specific inhibitor of the aspartate transcarbamylase activity of the multifunctional protein CAD, overproduce this protein as a result of amplification of the CAD gene. We have used a sensitive in situ hybridization technique...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Principais autores:	Wahl, G M, Vitto, L, Padgett, R A, Stark, G R
Formato:	Artigo
Idioma:	Inglês
Publicado:	Taylor & Francis 1982
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369790/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6180304/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.2.3.308-319.1982
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