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Nonhuman primate models and the failure of the Merck HIV-1 vaccine in humans

The recent announcement that a replication defective adenovirus-type 5 Gag-Pol-Nef HIV-1 vaccine developed by Merck failed in the STEP human Phase IIb efficacy trial to either prevent HIV-1 infection or to suppress viral load in subjects who subsequently became infected, was predicted by studies tha...

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Bibliografski detalji
Glavni autori: Watkins, David I., Burton, Dennis R., Kallas, Esper G., Moore, John P., Koff, Wayne C.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697853/
https://ncbi.nlm.nih.gov/pubmed/18535579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.f.1759
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