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Nonhuman primate models and the failure of the Merck HIV-1 vaccine in humans
The recent announcement that a replication defective adenovirus-type 5 Gag-Pol-Nef HIV-1 vaccine developed by Merck failed in the STEP human Phase IIb efficacy trial to either prevent HIV-1 infection or to suppress viral load in subjects who subsequently became infected, was predicted by studies tha...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3697853/ https://ncbi.nlm.nih.gov/pubmed/18535579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.f.1759 |
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