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Involvement of AAT transporters in methylmercury toxicity in Caenorhabditis elegans

Methylmercury (MeHg) is a potent neurotoxin that enters mammalian cells as a conjugate with L-cysteine through L-type large neutral amino acid transporter, LAT1, by a molecular mimicry mechanism by structurally resembling L-methionine. Caenorhabditis elegans (C. elegans) has been increasingly used t...

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Autors principals: Caito, Samuel W., Zhang, Yaofang, Aschner, Michael
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697847/
https://ncbi.nlm.nih.gov/pubmed/23669041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.04.090
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