Prolactin-deficient variants of GH3 rat pituitary tumor cells: linked expression of prolactin and another hormonally responsive protein in GH3 cells.

GH3 cells normally synthesize and secrete two pituitary polypeptide hormones, prolactin and growth hormone. From an ethyl methane sulfonate-mutagenized population, prolactin low-producing variants have been isolated at a frequency near 20%. Intracellular prolactin synthesis in the variants was reduc...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Ivarie, R D, Morris, J A, Martial, J A
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1982
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369771/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7110131/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.2.2.179
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