Pasteurella multocida Toxin as a Transporter of Non-Cell-Permeating Proteins

The protein toxin Pasteurella multocida toxin (PMT) is the causative agent of atrophic rhinitis in pigs, leading to atrophy of the nasal turbinate bones by affecting osteoblasts and osteoclasts. The mechanism of PMT-induced intoxication is a deamidation of α-subunits of heterotrimeric G proteins, in...

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Main Authors: Bergmann, Stefan, Jehle, Doris, Schwan, Carsten, Orth, Joachim H. C., Aktories, Klaus
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697606/
https://ncbi.nlm.nih.gov/pubmed/23630953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00429-13
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