Pasteurella multocida Toxin as a Transporter of Non-Cell-Permeating Proteins

The protein toxin Pasteurella multocida toxin (PMT) is the causative agent of atrophic rhinitis in pigs, leading to atrophy of the nasal turbinate bones by affecting osteoblasts and osteoclasts. The mechanism of PMT-induced intoxication is a deamidation of α-subunits of heterotrimeric G proteins, in...

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Главные авторы: Bergmann, Stefan, Jehle, Doris, Schwan, Carsten, Orth, Joachim H. C., Aktories, Klaus
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2013
Предметы:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697606/
https://ncbi.nlm.nih.gov/pubmed/23630953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00429-13
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