Anr and Its Activation by PlcH Activity in Pseudomonas aeruginosa Host Colonization and Virulence

Pseudomonas aeruginosa hemolytic phospholipase C (PlcH) degrades phosphatidylcholine (PC), an abundant lipid in cell membranes and lung surfactant. A ΔplcHR mutant, known to be defective in virulence in animal models, was less able to colonize epithelial cell monolayers and was defective in biofilm...

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Main Authors: Jackson, Angelyca A., Gross, Maegan J., Daniels, Emily F., Hampton, Thomas H., Hammond, John H., Vallet-Gely, Isabelle, Dove, Simon L., Stanton, Bruce A., Hogan, Deborah A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2013
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697539/
https://ncbi.nlm.nih.gov/pubmed/23667230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.02169-12
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