Expression of the RET Proto-oncogene Is Regulated by TFAP2C in Breast Cancer Independent of the Estrogen Receptor

BACKGROUND: The RET proto-oncogene is expressed as part of the estrogen receptor (ER) cluster in breast cancer. We sought to determine if TFAP2C regulates Ret expression directly or indirectly through ER. METHODS: Chromatin immunoprecipitation sequencing (ChIP-Seq) and gel-shift assay were used to i...

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Bibliographic Details
Main Authors: Spanheimer, Philip M., Woodfield, George W., Cyr, Anthony R., Kulak, Mikhail V., White-Baer, Lola S., Bair, Thomas B., Weigel, Ronald J.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697477/
https://ncbi.nlm.nih.gov/pubmed/22878616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-012-2570-5
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