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Vaccination with Lentiviral Vector Expressing the nfa1 Gene Confers a Protective Immune Response to Mice Infected with Naegleria fowleri

Naegleria fowleri, a pathogenic free-living amoeba, causes fatal primary amoebic meningoencephalitis (PAM) in humans and animals. The nfa1 gene (360 bp), cloned from a cDNA library of N. fowleri, produces a 13.1-kDa recombinant protein which is located on pseudopodia, particularly the food cup struc...

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Detalhes bibliográficos
Main Authors: Kim, Jong-Hyun, Sohn, Hae-Jin, Lee, Jinyoung, Yang, Hee-Jong, Chwae, Yong-Joon, Kim, Kyongmin, Park, Sun, Shin, Ho-Joon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697439/
https://ncbi.nlm.nih.gov/pubmed/23677321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00210-13
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