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Upregulation of PKCη by PKCε and PDK1 involves two distinct mechanisms and promotes breast cancer cell survival

BACKGROUND: Protein kinase C (PKC) serves as the receptor for tumor-promoting phorbol esters, which are potent activators of conventional (c) and novel (n) PKCs. We recently showed that these activators induced selective upregulation of PKCη in breast cancer cells. The objective of this study is to...

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Detalhes bibliográficos
Main Authors: Pal, Deepanwita, Outram, Shalini Persaud, Basu, Alakananda
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697430/
https://ncbi.nlm.nih.gov/pubmed/23562764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2013.03.028
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