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Human Simulated Studies of Aztreonam and Aztreonam-Avibactam To Evaluate Activity against Challenging Gram-Negative Organisms, Including Metallo-β-Lactamase Producers

Secondary to the stability of aztreonam against metallo-β-lactamases, coupled with avibatam's neutralizing activity against often coproduced extended-spectrum β-lactamases (ESBLs) or AmpC enzymes, the combination of aztreonam and avibactam has been proposed as a principal candidate for the trea...

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Bibliografiske detaljer
Main Authors: Crandon, Jared L., Nicolau, David P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697389/
https://ncbi.nlm.nih.gov/pubmed/23650162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01989-12
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