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RND-Type Efflux Pumps in Multidrug-Resistant Clinical Isolates of Acinetobacter baumannii: Major Role for AdeABC Overexpression and AdeRS Mutations

Increased expression of chromosomal genes for resistance-nodulation-cell division (RND)-type efflux systems plays a major role in the multidrug resistance (MDR) of Acinetobacter baumannii. However, the relative contributions of the three most prevalent pumps, AdeABC, AdeFGH, and AdeIJK, have not bee...

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Detalhes bibliográficos
Main Authors: Yoon, Eun-Jeong, Courvalin, Patrice, Grillot-Courvalin, Catherine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697384/
https://ncbi.nlm.nih.gov/pubmed/23587960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02556-12
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