Effect of Cardiopulmonary Bypass on Regional Antibiotic Penetration into Lung Tissue

The use of cardiopulmonary bypass (CPB) during cardiac surgery causes regional ventilation-perfusion mismatch, contributing to regional disturbances in antibiotic penetration into lung tissue. Ventilation-perfusion mismatch is associated with postoperative pneumonia, a frequent and devastating compl...

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Bibliographic Details
Main Authors: Hutschala, D., Skhirtladze, K., Kinstner, C., Zeitlinger, M., Wisser, W., Jaeger, W., Hoeferl, M., Müller, M., Tschernko, E.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697369/
https://ncbi.nlm.nih.gov/pubmed/23587954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02627-12
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