Candida glabrata Drug:H(+) Antiporter CgQdr2 Confers Imidazole Drug Resistance, Being Activated by Transcription Factor CgPdr1

The widespread emergence of antifungal drug resistance poses a severe clinical problem. Though predicted to play a role in this phenomenon, the drug:H(+) antiporters (DHA) of the major facilitator superfamily have largely escaped characterization in pathogenic yeasts. This work describes the first D...

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Hlavní autoři: Costa, Catarina, Pires, Carla, Cabrito, Tânia R., Renaudin, Adeline, Ohno, Michiyo, Chibana, Hiroji, Sá-Correia, Isabel, Teixeira, Miguel C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697362/
https://ncbi.nlm.nih.gov/pubmed/23629708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00811-12
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