Structural Analysis of the Role of Pseudomonas aeruginosa Penicillin-Binding Protein 5 in β-Lactam Resistance

Penicillin-binding protein 5 (PBP5) is one of the most abundant PBPs in Pseudomonas aeruginosa. Although its main function is that of a cell wall dd-carboxypeptidase, it possesses sufficient β-lactamase activity to contribute to the ability of P. aeruginosa to resist the antibiotic activity of the β...

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Hlavní autoři: Smith, Jeffrey D., Kumarasiri, Malika, Zhang, Weilie, Hesek, Dusan, Lee, Mijoon, Toth, Marta, Vakulenko, Sergei, Fisher, Jed F., Mobashery, Shahriar, Chen, Yu
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697341/
https://ncbi.nlm.nih.gov/pubmed/23629710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00505-13
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