Decreased Vancomycin Susceptibility in Staphylococcus aureus Caused by IS256 Tempering of WalKR Expression

Vancomycin-intermediate Staphylococcus aureus (VISA) strains often arise by mutations in the essential two-component regulator walKR; however their impact on walKR function has not been definitively established. Here, we investigated 10 MRSA strains recovered serially after exposure of vancomycin-su...

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Bibliographic Details
Main Authors: McEvoy, Christopher R. E., Tsuji, Brian, Gao, Wei, Seemann, Torsten, Porter, Jessica L., Doig, Kenneth, Ngo, Dung, Howden, Benjamin P., Stinear, Timothy P.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697332/
https://ncbi.nlm.nih.gov/pubmed/23629723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00279-13
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