Nonrandomized Controlled Trial of Artesunate plus Sulfadoxine-Pyrimethamine with or without Primaquine for Preventing Posttreatment Circulation of Plasmodium falciparum Gametocytes

Artemisinin combination therapies eliminate immature Plasmodium falciparum gametocytes but not mature gametocytes, which may persist for up to 1 month posttreatment. A single dose of primaquine, which is inexpensive and effective against mature gametocytes, could be added to further reduce the poten...

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Autores principales: Shah, Naman K., Schapira, Allan, Juliano, Jonathan J., Srivastava, Bina, MacDonald, Pia D. M., Poole, Charles, Anvikar, Anup, Meshnick, Steven R., Valecha, Neena, Mishra, Neelima
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
Materias:
Clinical Therapeutics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697316/
https://ncbi.nlm.nih.gov/pubmed/23587943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00139-13
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