Nonrandomized Controlled Trial of Artesunate plus Sulfadoxine-Pyrimethamine with or without Primaquine for Preventing Posttreatment Circulation of Plasmodium falciparum Gametocytes

Artemisinin combination therapies eliminate immature Plasmodium falciparum gametocytes but not mature gametocytes, which may persist for up to 1 month posttreatment. A single dose of primaquine, which is inexpensive and effective against mature gametocytes, could be added to further reduce the poten...

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Bibliographische Detailangaben
Hauptverfasser: Shah, Naman K., Schapira, Allan, Juliano, Jonathan J., Srivastava, Bina, MacDonald, Pia D. M., Poole, Charles, Anvikar, Anup, Meshnick, Steven R., Valecha, Neena, Mishra, Neelima
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Clinical Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697316/
https://ncbi.nlm.nih.gov/pubmed/23587943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00139-13
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