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The antibiotics doxycycline and minocycline inhibit inflammatory responses to the Lyme disease spirochete Borrelia burgdorferi

Tetracyclines moderate inflammatory responses of various etiologies. We hypothesized that tetracyclines exerted, in addition to antimicrobial function, control over inflammation elicited by Borrelia burgdorferi. To model systemic effects we used the human monocytic cell line THP-1, and for effects i...

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Hlavní autoři: Bernardino, Andrea L. F., Kaushal, Deepak, Philipp, Mario T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697124/
https://ncbi.nlm.nih.gov/pubmed/19301981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/597807
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