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Synaptic transmission and the susceptibility of HIV infection to anti-viral drugs

Cell-to-cell viral transmission via virological synapses has been argued to reduce susceptibility of the virus population to anti-viral drugs through multiple infection of cells, contributing to low-level viral persistence during therapy. Using a mathematical framework, we examine the role of synapt...

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Detalhes bibliográficos
Main Authors: Komarova, Natalia L., Levy, David N., Wodarz, Dominik
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696900/
https://ncbi.nlm.nih.gov/pubmed/23811684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02103
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