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Segregation of recessive phenotypes in somatic cell hybrids: role of mitotic recombination, gene inactivation, and chromosome nondisjunction.

Somatic cell hybrids heterozygous at the emetine resistance locus (emtr/emt+) or the chromate resistance locus (chrr/chr+) are known to segregate the recessive drug resistance phenotype at high frequency. We have examined mechanisms of segregation in Chinese hamster cell hybrids heterozygous at thes...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Principais autores: Campbell, C E, Worton, R G
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 1981
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369682/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6965251/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.1.4.336-346.1981
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