Langerin(neg) conventional dendritic cells produce IL-23 to drive psoriatic plaque formation in mice

Psoriasis is an autoinflammatory skin disease of unknown etiology. Topical application of Aldara cream containing the Toll-like receptor (TLR)7 agonist Imiquimod (IMQ) onto patients induces flares of psoriasis. Likewise, in mice IMQ triggers pathological changes closely resembling psoriatic plaque f...

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Hlavní autoři: Wohn, Christian, Ober-Blöbaum, Julia L., Haak, Stefan, Pantelyushin, Stanislav, Cheong, Cheolho, Zahner, Sonja P., Onderwater, Sabina, Kant, Marius, Weighardt, Heike, Holzmann, Bernhard, Reizis, Boris, Becher, Burkhard, Prens, Errol P., Clausen, Björn E.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696803/
https://ncbi.nlm.nih.gov/pubmed/23754427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307569110
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