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Staphylococcus aureus LukAB cytotoxin kills human neutrophils by targeting the CD11b subunit of the integrin Mac-1

Staphylococcus aureus causes diseases ranging from superficial wound infections to more invasive manifestations like osteomyelitis and endocarditis. The evasion of host phagocytes recruited to the site of infection is essential to the success of S. aureus as a pathogen. A single S. aureus strain can...

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Autori principali: DuMont, Ashley L., Yoong, Pauline, Day, Christopher J., Alonzo, Francis, McDonald, W. Hayes, Jennings, Michael P., Torres, Victor J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696772/
https://ncbi.nlm.nih.gov/pubmed/23754403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1305121110
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