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Parathyroid Hormone-Related Protein Specifies the Mammary Mesenchyme and Regulates Embryonic Mammary Development

Parathyroid Hormone related Protein (PTHrP) is a critical regulator of mammary gland morphogenesis in the mouse embryo. Loss of PTHrP, or its receptor, PTHR1, results in arrested mammary buds at day 15 of embryonic development (E15). In contrast, overexpression of PTHrP converts the ventral epidermi...

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Détails bibliographiques
Auteurs principaux: Hiremath, Minoti, Wysolmerski, John
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696739/
https://ncbi.nlm.nih.gov/pubmed/23640717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10911-013-9283-7
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