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Bromodeoxyuridine mutagenesis in mammalian cells is related to deoxyribonucleotide pool imbalance.

The relationship between bromodeoxyuridine (BrdUrd) mutagenesis in mammalian cells and the effects of BrdUrd on deoxyribonucleoside triphosphate pools was analyzed. It was found that the exposure of Syrian hamster melanoma cells to mutagenic concentrations of BrdUrd resulted in the formation of a la...

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Detalles Bibliográficos
Main Authors: Ashman, C R, Davidson, R L
Formato: Artigo
Idioma:Inglês
Publicado: 1981
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC369669/
https://ncbi.nlm.nih.gov/pubmed/6965099
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